Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene

Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene

<p>Background: Substance P (SP) is a pain- and inflammation-related neuropeptide which preferentially binds to the neurokinin receptor 1 (NK1). SP and NK1 receptors have been implicated in joint pain, inflammation and damage in animal models and human studies of osteoarthritis (OA). The aim o...

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Opis bibliograficzny
Główni autorzy: Warner, S, Walsh, D, Laslett, L, Maciewicz, R, Soni, A, Hart, D, Zhang, W, Muir, K, Dennison, E, Leaverton, P, Rampersaud, E, Cooper, C, Spector, T, Cicuttini, F, Arden, N, Jones, G, Doherty, M, Valdes, A
Format: Journal article
Wydane: Wiley 2017

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