Coarse-grained simulations of DNA overstretching.

We use a recently developed coarse-grained model to simulate the overstretching of duplex DNA. Overstretching at 23 degrees C occurs at 74 pN in the model, about 6-7 pN higher than the experimental value at equivalent salt conditions. Furthermore, the model reproduces the temperature dependence of t...

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Bibliographic Details
Main Authors: Romano, F, Chakraborty, D, Doye, J, Ouldridge, T, Louis, A
Format: Journal article
Language:English
Published: American Institute of Physics 2013