Coarse-grained simulations of DNA overstretching.
We use a recently developed coarse-grained model to simulate the overstretching of duplex DNA. Overstretching at 23 degrees C occurs at 74 pN in the model, about 6-7 pN higher than the experimental value at equivalent salt conditions. Furthermore, the model reproduces the temperature dependence of t...
Main Authors: | , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
American Institute of Physics
2013
|