Normal development and function of T cells in proline rich 7 (Prr7) deficient mice
Transmembrane adaptor proteins (TRAPs) are important organisers for the transduction of immunoreceptor-mediated signals. Prr7 is a TRAP that regulates T cell receptor (TCR) signalling and potently induces cell death when overexpressed in human Jurkat T cells. Whether endogenous Prr7 has a similar fu...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Public Library of Science
2016
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