T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire.

Mouse type I natural killer T cell receptors (iNKT TCRs) use a single V alpha 14-J alpha 18 sequence and V beta s that are almost always V beta 8.2, V beta 7, or V beta 2, although the basis of this differential usage is unclear. We showed that the V beta bias occurred as a consequence of the CDR2 b...

詳細記述

書誌詳細
主要な著者: Mallevaey, T, Scott-Browne, J, Matsuda, J, Young, M, Pellicci, D, Patel, O, Thakur, M, Kjer-Nielsen, L, Richardson, S, Cerundolo, V, Howell, A, McCluskey, J, Godfrey, D, Rossjohn, J, Marrack, P, Gapin, L
フォーマット: Journal article
言語:English
出版事項: 2009