CD28 affects the earliest signaling events generated by TCR engagement.

The efficiency and magnitude of T cell responses are influenced by ligation of the co-stimulatory receptor CD28 by B7 molecules expressed on antigen-presenting cells (APC). In contrast to most previous studies in which agonistic anti-TCR/CD3 and anti-CD28 antibodies were employed, here we have inves...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Tuosto, L, Acuto, O
Format: Journal article
Język:English
Wydane: 1998