CD28 affects the earliest signaling events generated by TCR engagement.
The efficiency and magnitude of T cell responses are influenced by ligation of the co-stimulatory receptor CD28 by B7 molecules expressed on antigen-presenting cells (APC). In contrast to most previous studies in which agonistic anti-TCR/CD3 and anti-CD28 antibodies were employed, here we have inves...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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