Using progenitor strain information to identify quantitative trait nucleotides in outbred mice.

We have developed a fast and economical strategy for dissecting the genetic architecture of quantitative trait loci at a molecular level. The method uses two pieces of information: mapping data from crosses that involve more than two inbred strains and sequence variants in the progenitor strains wit...

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Bibliographic Details
Main Authors: Yalcin, B, Flint, J, Mott, R
Format: Journal article
Language:English
Published: 2005