Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

Several strands of evidence question the dogma that human mitochondrial DNA (mtDNA) is inherited exclusively down the maternal line, most recently in three families where several individuals harbored a 'heteroplasmic haplotype' consistent with biparental transmission. Here we report a simi...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Wei, W, Pagnamenta, AT, Gleadall, N, Sanchis-Juan, A, Stephens, J, Broxholme, J, Tuna, S, Odhams, CA, Genomics England Research Consortium, NIHR BioResource, Fratter, C, Turro, E, Caulfield, MJ, Taylor, JC, Rahman, S, Chinnery, PF
Formaat: Journal article
Taal:English
Gepubliceerd in: Springer Nature 2020