A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate

Diphosphoinositol phosphates (PP-InsPs) are inositol phosphates (InsPs) that contain PP (diphosphate) groups. Converting a phosphate group in an InsP into a diphosphate has been reported to enhance affinity for some binding proteins. We synthesised 1-PP-Ins(4,5)P2, the first diphosphate analogue of...

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Bibliographic Details
Main Authors: Riley, A, Unterlass, J, Konieczny, V, Taylor, C, Potter, B
Format: Journal article
Published: Royal Society of Chemistry 2018