Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics.

Crohn disease (CD) is a chronic relapsing inflammatory condition of the gastrointestinal tract. Recently, polymorphisms in NOD2 (CARD15), a gene mapping to the chromosome 16 IBD1 susceptibility locus, have been associated with susceptibility to CD. One group identified the gene by using classic posi...

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Bibliographic Details
Main Authors: van Heel, D, McGovern, D, Cardon, L, Dechairo, B, Lench, N, Carey, A, Jewell, D
Format: Journal article
Language:English
Published: 2002