Enantioconvergent alkylation of ketones with racemic secondary alcohols via hydrogen borrowing catalysis

Enantioconvergent alkylation of ketones with racemic secondary alcohols via hydrogen borrowing catalysis

An enantioconvergent method for the alkylation of o-disubstituted aryl ketones with racemic secondary alcohols is described. This process is mediated by a commercially available iridium catalyst and proceeds via hydrogen borrowing catalysis. The highly enantioenriched β-substituted ketone products w...

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Dettagli Bibliografici
Autori principali:	Cheang, DMJ, Armstrong, RJ, Akhtar, WM, Donohoe, TJ
Natura:	Journal article
Lingua:	English
Pubblicazione:	Royal Society of Chemistry 2020

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