Computational methods for the study of immunoglobulin aggregation

<p>Protein aggregation is a major challenge in the development of antibody-based therapeutics. Therapeutic antibodies are produced and stored in high concentrations and under fluctuating conditions unfavourable for their stability. Aggregation of these proteins in solution leads to serious con...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Shorthouse, DR
مؤلفون آخرون: Sansom, MSP
التنسيق: أطروحة
اللغة:English
منشور في: 2015
الموضوعات: