Correlation of tolerogenicity of a viral antigen with its immunogenicity.
Induction of B cell tolerance or activation was analyzed with vesicular stomatitis virus (VSV) glycoprotein (G) expressed as a neo-self Ag. A membrane form of VSV-G expressed in all tissues, including the bone marrow, induced unresponsiveness at both the Th and B cell level, whereas a soluble form o...
Main Authors: | , , , , |
---|---|
格式: | Journal article |
語言: | English |
出版: |
1997
|