Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.

There is an urgent need for new antimalarial drugs with novel mechanisms of action to deliver effective control and eradication programs. Parasite resistance to all existing antimalarial classes, including the artemisinins, has been reported during their clinical use. A failure to generate new antim...

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Manylion Llyfryddiaeth
Prif Awduron: Biagini, G, Fisher, N, Shone, A, Mubaraki, M, Srivastava, A, Hill, A, Antoine, T, Warman, A, Davies, J, Pidathala, C, Amewu, R, Leung, S, Sharma, R, Gibbons, P, Hong, D, Pacorel, B, Lawrenson, A, Charoensutthivarakul, S, Taylor, L, Berger, O, Mbekeani, A, Stocks, P, Nixon, G, Chadwick, J, Hemingway, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2012

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