An autonomous oscillator times and executes centriole biogenesis
The accurate timing and execution of organelle biogenesis is crucial for cell physiology. Centriole biogenesis is regulated by Polo-like kinase 4 (Plk4) and initiates in S-phase when a daughter centriole grows from the side of a preexisting mother. Here we show that Plk4 forms an adaptive oscillator...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Cold Spring Harbor Laboratory
2019
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