Adjuvant effects elicited by novel oligosaccharide variants of detoxified meningococcal lipopolysaccharides on neisseria meningitidis recombinant porA protein: a comparison in mice

Neisseria meningitidis lipopolysaccharide (LPS) has adjuvant properties that can be exploited to assist vaccine immunogenicity. The modified penta-acylated LPS retains the adjuvant properties of hexa-acylated LPS but has a reduced toxicity profile. In this study we investigated whether two modified...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Mehta, O, Norheim, G, Hoe, J, Rollier, C, Nagaputra, J, Makepeace, K, Saleem, M, Chan, H, Ferguson, D, Jones, C, Sadarangani, M, Hood, D, Feavers, I, Derrick, J, Pollard, A, Moxon, E
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Public Library of Science 2014