DIRECT OBSERVATION OF A TETRAHEDRAL BORONIC ACID BETA-LACTAMASE COMPLEX USING B-11 NMR-SPECTROSCOPY

A tetrahedral boronic acid-β-lactamase complex formed by treatment of the P99 β-lactamase enzyme from Enterobacter cloacae with 3-dansylamidophenylboronic acid has been directly observed using 11B NMR spectroscopy.

Dettagli Bibliografici
Autori principali: Baldwin, J, Claridge, T, Derome, A, Smith, B, Twyman, M, Waley, S
Natura: Journal article
Pubblicazione: 1991
Descrizione
Riassunto:A tetrahedral boronic acid-β-lactamase complex formed by treatment of the P99 β-lactamase enzyme from Enterobacter cloacae with 3-dansylamidophenylboronic acid has been directly observed using 11B NMR spectroscopy.