Ion channel gating: insights via molecular simulations.

Ion channels are gated, i.e. they can switch conformation between a closed and an open state. Molecular dynamics simulations may be used to study the conformational dynamics of ion channels and of simple channel models. Simulations on model nanopores reveal that a narrow (<4 A) hydrophobic re...

Full description

Bibliographic Details
Main Authors: Beckstein, O, Biggin, P, Bond, P, Bright, J, Domene, C, Grottesi, A, Holyoake, J, Sansom, MS
Format: Journal article
Language:English
Published: 2003