Ion channel gating: insights via molecular simulations.
Ion channels are gated, i.e. they can switch conformation between a closed and an open state. Molecular dynamics simulations may be used to study the conformational dynamics of ion channels and of simple channel models. Simulations on model nanopores reveal that a narrow (<4 A) hydrophobic re...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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