Differential effects of PCSK9 variants on risk of coronary disease and ischaemic stroke

<strong>Aims:</strong> PCSK9 genetic variants that have large effects on low density lipoprotein cholesterol (LDL-C) and coronary heart disease (CHD) have prompted the development of therapeutic PCSK9-inhibition. However, there is limited evidence that PCSK9 variants are associated with...

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Autori principali: Hopewell, J, Malik, R, Valdes-Marquez, E, Worrall, B, Collins, R, METASTROKE Collaboration of the ISGC
Natura: Journal article
Pubblicazione: Oxford University Press 2017