Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720.

ICC-1132, a recombinant virus-like particle comprising of a modified hepatitis B core protein with a B cell (NANP) and two T cell epitopes of Plasmodium falciparum circumsporozoite protein (CSP), was administered i.m. as a single 50 microg dose in Seppic ISA 720 to 11 volunteers. Local reactogenicit...

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Bibliographic Details
Main Authors:	Walther, M, Dunachie, S, Keating, S, Vuola, J, Berthoud, T, Schmidt, A, Maier, C, Andrews, L, Andersen, R, Gilbert, S, Poulton, I, Webster, D, Dubovsky, F, Tierney, E, Sarpotdar, P, Correa, S, Huntcooke, A, Butcher, G, Williams, J, Sinden, R, Thornton, G, Hill, A
Format:	Journal article
Language:	English
Published:	2005

Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720.

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