Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells

Despite the well-established cell-intrinsic role of epigenetic factors in normal and malignant hematopoiesis, their cell-extrinsic role remains largely unexplored. Herein we investigated the hematopoietic impact of inactivating Ezh2, a key component of polycomb repressive complex 2 (PRC2), in the fe...

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Detalhes bibliográficos
Principais autores: Neo, W, Booth, C, Azzoni, E, Chi, L, Delgado-Olguin, P, de Bruijn, M, Jacobsen, S, Mead, A
Formato: Journal article
Publicado em: American Society of Hematology 2018