Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts.

BACKGROUND: Triple nucleoside reverse transcriptase inhibitor regimens have advantages as first-line antiretroviral therapy (ART), avoiding hepatotoxicity and interactions with anti-tuberculosis therapy, and sparing two drug classes for second-line ART. Concerns exist about virological potency; effi...

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Bibliographic Details
Main Authors: Munderi, P, Walker, A, Kityo, C, Babiker, A, Ssali, F, Reid, A, Darbyshire, J, Grosskurth, H, Mugyenyi, P, Gibb, D, Gilks, C
Format: Journal article
Language:English
Published: 2010