Evaluation of metal-mediated DNA binding of benzoxazole ligands by electrospray ionization mass spectrometry.

The binding of a series of benzoxazole analogs with different amide- and ester-linked side chains to duplex DNA in the absence and presence of divalent metal cations is examined. All ligands were found to form complexes with Ni2+, Cu2+, and Zn2+, with 2:1 ligand/metal cation binding stoichiometries...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Mazzitelli, C, Rodriguez, M, Kerwin, S, Brodbelt, J
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2008