Evaluation of metal-mediated DNA binding of benzoxazole ligands by electrospray ionization mass spectrometry.
The binding of a series of benzoxazole analogs with different amide- and ester-linked side chains to duplex DNA in the absence and presence of divalent metal cations is examined. All ligands were found to form complexes with Ni2+, Cu2+, and Zn2+, with 2:1 ligand/metal cation binding stoichiometries...
Egile Nagusiak: | , , , |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2008
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