Mitochondria are selectively eliminated from eukaryotic cells after blockade of caspases during apoptosis.

Pan caspase inhibitors are potentially powerful cell-protective agents that block apoptosis in response to a wide variety of insults that cause tissue degeneration. In many conditions, however, the blockade of apoptosis by caspase inhibitors does not permit long-term cell survival, but the reasons a...

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Bibliographic Details
Main Authors: Xue, L, Fletcher, G, Tolkovsky, A
Format: Journal article
Language:English
Published: 2001