Transfection of thyroid autoantigens into EBV-transformed B cell lines. Recognition by Graves' disease thyroid T cells.

Autologous EBV-transformed B cell lines (EBVL) from a patient with Graves' disease (GD) were transfected with the expression vector pREP4 encoding thyroid peroxidase (TPO), the thyroid-stimulating hormone receptor (TSHR), or chloramphenicol acetyl transferase. The relevant proteins were express...

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Autors principals: Mullins, R, Chernajovsky, Y, Dayan, C, Londei, M, Feldmann, M
Format: Journal article
Idioma:English
Publicat: 1994

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