Enzymatic amplification of exogenous and endogenous retroviral sequences from DNA of patients with tropical spastic paraparesis.

Using oligonucleotide primers that hybridize to conserved sequences in the reverse transcriptase (RT) gene, we have amplified by the polymerase chain reaction three sequence variants of HTLV-I from the genomic DNA of five patients with tropical spastic paraparesis (TSP), and a fourth sequence varian...

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Bibliographic Details
Main Authors: Bangham, C, Daenke, S, Phillips, R, Cruickshank, J, Bell, J
Format: Journal article
Language:English
Published: 1988