Sperm chromatin: evaluation, epigenetic signatures and relevance for embryo development and assisted reproductive technology outcomes

Sperm chromatin is distinct from somatic cell chromatin, as a result of extensive remodeling during the final stages of spermatogenesis. In this process, the majority of histones is replaced with protamines. The chromatin is consequently highly condensed and inert, which facilitates protection of th...

Полное описание

Библиографические подробности
Главные авторы: Balder, P, Jones, C, Coward, K, Yeste, M
Формат: Journal article
Язык:English
Опубликовано: Elsevier 2024