Small-molecule inhibitors and probes for ubiquitin- and ubiquitin-like-specific proteases.

There's always a catch. The post-translational modification of proteins with ubiquitin (Ub) or ubiquitin-like (Ubl) modifiers is an important signal in the regulation of a variety of biological processes, such as degradation and regulation of gene expression. Here we report the synthesis of a p...

Full description

Bibliographic Details
Main Authors: Borodovsky, A, Ovaa, H, Meester, W, Venanzi, E, Bogyo, MS, Hekking, BG, Ploegh, H, Kessler, B, Overkleeft, H
Format: Journal article
Language:English
Published: 2005