Small-molecule inhibitors and probes for ubiquitin- and ubiquitin-like-specific proteases.
There's always a catch. The post-translational modification of proteins with ubiquitin (Ub) or ubiquitin-like (Ubl) modifiers is an important signal in the regulation of a variety of biological processes, such as degradation and regulation of gene expression. Here we report the synthesis of a p...
Hauptverfasser: | Borodovsky, A, Ovaa, H, Meester, W, Venanzi, E, Bogyo, MS, Hekking, BG, Ploegh, H, Kessler, B, Overkleeft, H |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2005
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