Recognition of CpG island chromatin by KDM2A requires direct and specific interaction with linker DNA.

Recognition of CpG island chromatin by KDM2A requires direct and specific interaction with linker DNA.

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Up to 70% of human genes are associated with regions of nonmethylated DNA called CpG islands (S. Saxonov, P. Berg, and D. L. Brutlag, Proc. Natl. Acad. Sci. U. S. A. 103:1412-1417, 2006). Usually associated with the 5' end of genes, CpG islands are thought to impact gene expression. We previous...

Полное описание

Библиографические подробности
Главные авторы:	Zhou, J, Blackledge, N, Farcas, A, Klose, R
Формат:	Journal article
Язык:	English
Опубликовано:	2012

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