Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset.

Hepatitis C virus (HCV) is associated with the B-cell lymphoproliferative disorders mixed cryoglobulinemia (MC) and non-Hodgkin lymphoma. We have previously reported that HCV(+)MC(+) patients have clonal expansions of hypermutated, rheumatoid factor-bearing marginal zone-like IgM(+)CD27(+) periphera...

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Bibliographic Details
Main Authors: Charles, E, Brunetti, C, Marukian, S, Ritola, K, Talal, A, Marks, K, Jacobson, I, Rice, C, Dustin, L
Format: Journal article
Language:English
Published: 2011