Phenotypic models of T cell activation.
T cell activation is a crucial checkpoint in adaptive immunity, and this activation depends on the binding parameters that govern the interactions between T cell receptors (TCRs) and peptide-MHC complexes (pMHC complexes). Despite extensive experimental studies, the relationship between the TCR-pMHC...
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2014
|