Phenotypic models of T cell activation.

T cell activation is a crucial checkpoint in adaptive immunity, and this activation depends on the binding parameters that govern the interactions between T cell receptors (TCRs) and peptide-MHC complexes (pMHC complexes). Despite extensive experimental studies, the relationship between the TCR-pMHC...

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Bibliographic Details
Main Authors: Lever, M, Maini, P, Van Der Merwe, P, Dushek, O
Format: Journal article
Language:English
Published: Nature Publishing Group 2014