Mitotic kinase oscillation governs the latching of cell cycle switches

In 1996, Kim Nasmyth1 proposed that the eukaryotic cell cycle is an alternating sequence of transitions from G1 to S-G2-M and back again. These two phases correlate to high activity of cyclin-dependent kinases (CDKs) that trigger S-G2-M events and CDK antagonists that stabilize G1 phase. We associat...

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Bibliographic Details
Main Authors: Novak, B, Tyson, JJ
Format: Journal article
Language:English
Published: Cell Press 2022