A SHORT APPROACH TO FUNCTIONALIZED HOMOCHIRAL PIPERIDINONES
The preparation of homochiral lactam 4 in 5 steps from (S)-lysine is described. Convenion to bicyclic O,N-acetal 5 provides a useful template for further elaboration to highly substituted piperidinones with excellent diastereoselectivity. © 1994.
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1994
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