Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal

Metabolic dysfunction of endothelial cells in hyperglycemia contributes to the development of vascular complications of diabetes where increased reactive glycating agent, methylglyoxal (MG), is involved. We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Irshad, Z, Xue, M, Ashour, A, Larkin, JR, Thornalley, PJ, Rabbani, N
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Springer Nature 2019