Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Metabolic dysfunction of endothelial cells in hyperglycemia contributes to the development of vascular complications of diabetes where increased reactive glycating agent, methylglyoxal (MG), is involved. We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic...
Main Authors: | Irshad, Z, Xue, M, Ashour, A, Larkin, JR, Thornalley, PJ, Rabbani, N |
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格式: | Journal article |
语言: | English |
出版: |
Springer Nature
2019
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