Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal

Metabolic dysfunction of endothelial cells in hyperglycemia contributes to the development of vascular complications of diabetes where increased reactive glycating agent, methylglyoxal (MG), is involved. We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic...

書誌詳細
主要な著者:	Irshad, Z, Xue, M, Ashour, A, Larkin, JR, Thornalley, PJ, Rabbani, N
フォーマット:	Journal article
言語:	English
出版事項:	Springer Nature 2019

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