Pyruvate enolate arylation and alkylation: OBO ester protected pyruvates as useful reagents in organic synthesis

A protected pyruvate equivalent is described that allows arylation and arylation/alkylation reactions to be performed at the methyl group. Utilization of the OBO derivative of the pyruvate ester allowed the application of palladium catalyzed arylation reactions together with subsequent alkylation, u...

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Bibliographic Details
Main Authors: Alves Esteves, C, Hall, C, Smith, P, Donohoe, T
Format: Journal article
Language:English
Published: American Chemical Society 2017