Pyruvate enolate arylation and alkylation: OBO ester protected pyruvates as useful reagents in organic synthesis

A protected pyruvate equivalent is described that allows arylation and arylation/alkylation reactions to be performed at the methyl group. Utilization of the OBO derivative of the pyruvate ester allowed the application of palladium catalyzed arylation reactions together with subsequent alkylation, u...

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Príomhchruthaitheoirí: Alves Esteves, C, Hall, C, Smith, P, Donohoe, T
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: American Chemical Society 2017