Investigation of osteoclastogenic signalling of the RANKL substitute LIGHT.
LIGHT (TNFSF14) is a member of the TNF superfamily and is known to substitute for RANKL to induce osteoclast differentiation. LIGHT binds HVEM and LTβR, but it is not known whether these receptors play a role in osteoclast formation or whether LIGHT acts via RANKL signalling pathways. We found that...
Hlavní autoři: | Hemingway, F, Kashima, T, Knowles, H, Athanasou, N |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2013
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