Investigation of osteoclastogenic signalling of the RANKL substitute LIGHT.
LIGHT (TNFSF14) is a member of the TNF superfamily and is known to substitute for RANKL to induce osteoclast differentiation. LIGHT binds HVEM and LTβR, but it is not known whether these receptors play a role in osteoclast formation or whether LIGHT acts via RANKL signalling pathways. We found that...
Prif Awduron: | , , , |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2013
|