Efficient protein production inspired by how spiders make silk.
Membrane proteins are targets of most available pharmaceuticals, but they are difficult to produce recombinantly, like many other aggregation-prone proteins. Spiders can produce silk proteins at huge concentrations by sequestering their aggregation-prone regions in micellar structures, where the ver...
Main Authors: | Kronqvist, N, Sarr, M, Lindqvist, A, Nordling, K, Otikovs, M, Venturi, L, Pioselli, B, Purhonen, P, Landreh, M, Biverstål, H, Toleikis, Z, Sjöberg, L, Robinson, C, Pelizzi, N, Jörnvall, H, Hebert, H, Jaudzems, K, Curstedt, T, Rising, A, Johansson, J |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2017
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