A mechanism for initiating RNA-dependent RNA polymerization.

In most RNA viruses, genome replication and transcription are catalysed by a viral RNA-dependent RNA polymerase. Double-stranded RNA viruses perform these operations in a capsid (the polymerase complex), using an enzyme that can read both single- and double-stranded RNA. Structures have been solved...

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Bibliographic Details
Main Authors: Butcher, S, Grimes, J, Makeyev, E, Bamford, D, Stuart, D
Format: Journal article
Language:English
Published: 2001