Asymmetric synthesis of syn- and anti-alpha-deuterio-beta(3)-phenylalanine derivatives
The conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl) amide to a range of aryl substituted tert-butyl cinnamate esters followed by reaction of the resultant lithium β-amino enolates with D2O provides access to anti configured α-deuterio-β-aminocinnamate esters in high dr. The correspondi...
| Hoofdauteurs: | , , , , , , |
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
2011
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