Modulation of dendritic cell endocytosis and antigen processing pathways by Escherichia coli heat-labile enterotoxin and mutant derivatives.

Escherichia coli heat-labile enterotoxin (LT) is known to be a potent adjuvant of both the mucosal and systemic immune systems but the mechanism of action leading to adjuvant activity remains incompletely understood. This study investigates the action of LT and LT mutants with impaired enzymatic act...

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Bibliographic Details
Main Authors: Petrovska, L, Lopes, L, Simmons, C, Pizza, M, Dougan, G, Chain, B
Format: Journal article
Language:English
Published: 2003