Epoxides related to dioncoquinone B: Synthesis, activity against multiple myeloma cells, and search for the target protein
Epoxide 2b is an analog of the synthetic intermediate 2a en route to the polyketide-derived antitumoral naphthoquinone dioncoquinone B (1), isolated from cell cultures of the tropical liana Triphyophyllum peltatum (Dioncophyllaceae). Compound 2b was found to induce strong apoptosis in multiple myelo...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Published: |
Elsevier
2018
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