Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors.

Tissue inhibitors of metalloproteinases (TIMPs) are important regulators of matrix metalloproteinase (MMP) and adamalysin (ADAM) activity. We have previously shown that adenovirally expressed tissue inhibitor of metalloproteinases-3 (TIMP-3) induces apoptosis in melanoma cells and inhibits growth of...

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Bibliographic Details
Main Authors: Ahonen, M, Poukkula, M, Baker, A, Kashiwagi, M, Nagase, H, Eriksson, J, Kähäri, V
Format: Journal article
Language:English
Published: 2003