A study of the phenotype and function of HLA-C restricted CD8 T cells in HIV-1 infection

<p>A recent study showed that a polymorphism ~35kb upstream of the HLA-C gene (-35 SNP) correlates with host control of HIV-1 in Caucasians, with the minor allele (C) associating with significantly lower set point viral loads than the major allele (T). A link between viral load and HLA-C is s...

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Bibliographic Details
Main Author: Corrah, TW
Other Authors: McMichael, A
Format: Thesis
Language:English
Published: 2011
Subjects: