The toll-like receptor-nuclear factor kappaB pathway in rheumatoid arthritis.
The study of the role cytokines play in the pathogenesis of rheumatoid arthritis (RA) has provided a whole new range of targets for drug development. Many of them (e.g. TNF, IL-1, IL-6, IL-15 and IL-18) are already being targeted in the clinic with success using neutralizing monoclonal antibodies or...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Jezik: | English |
| Izdano: |
2005
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