PCSK9 inhibition: the dawn of a new age in cholesterol lowering?
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a circulating enzyme of hepatic origin which plays a key role in low density lipoprotein (LDL) receptor turnover. Genetic studies have confirmed that those with gain-of-function PCSK9 mutations have increased PCSK9 activity, elevated LDLcholes...
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| Format: | Journal article |
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Springer Berlin Heidelberg
2016
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